The Southern Kings have named their team to face the Stormers in Cape Town with Luke Watson missing the game due to flu.
The Kings management delayed the announcement of their team for the game until Thursday, which allowed star flyhalf Demetri Catrakilis time to recover from a leg injury. Watson, however, will sit this one out.
"Luke has flu and is not great," said Kings director of rugby Alan Solomons.
"He hasn't been able to practice and on medical advice he will not be playing."
Watson's spot in the loose forward trio will be taken by Jacques Engelbrecht, with Devin Oosthuizen moving to the bench.
Injuries have resulted in two other changes to the side, with wing Siyanda Grey and experienced lock Steven Sykes sidelined for several weeks.
Young wing Siviwe Soyiwapi fills Grey's spot while veteran lock Darron Nell should prove a useful replacement for Sykes.
In a rotational move, the Kings have decided to give Argentine scrumhalf Nicolas Vergallo a start, with regular number nine Shaun Venter moving to the bench.
With wet weather set to hit Cape Town this weekend, Solomons predicted a tough forward battle.
"I have lived in Cape Town and when you get a series of fronts it can get really bad, so I think the Stormers will be concentrating on a solid kicking game and play for territory."
Solomons felt the tactical kicking duel would be a major factor in the match.
"We have worked hard on our kicking game and up front it will be critical for our pack to front up. I have no doubt they will," he said.
"Most of them have played together in many games this season and we have every confidence they will be up for the challenge."
15. SP Marais , 14. Siviwe Soyizwapi ,, 13. Ronnie Cooke , 12. Andries Strauss (Captain), 11. Marcello Sampson , 10. Demetri Catrakilis , 9. Nicolas Vergallo , 8. Jacques Engelbrecht , 7. Wimpie van der Walt, 6. Cornell du Preez, 5. David Bulbring , 4. Darron Nell (Vice Captain) , 3. Kevin Buys , 2. Bandise Maku , 1. Schalk Ferreira
Replacements : 16. Hannes Franklin , 17. Grant Kemp , 18. Rynier Bernado , 19. Devin Oosthuizen , 20. Shaun Venter , 21. Shane Gates , 22. George Whitehead