The Sharks and the Southern Kings will only be playing for pride in Durban as they are both out of the running for this year's Super Rugby title.
For The Sharks, it's the final match of an unsatisfactory season where they went from runners-up in 2012 to being all but eliminated from the playoffs before the June Test break.
After this weekend, the Kings still have two very crucial matches left, as they prepare to face the Lions in two promotion/relegation matches.
The Kings will be travelling to Durban with a lot of fringe players in the starting line-up as the decision was taken to rest all their first-choice players carrying injury niggles this week.
And that could be the catalyst the visitors need as the selected players will be out to impress.
The last time these two teams met, the Sharks left Port Elizabeth on the back of a 21-12 victory in a match that ended try-less.
In the history of Super Rugby, that is something that has only happened four times in South African derbies - and The Sharks were involved in three of these encounters.
For Hugh Reece-Edwards, co-coach of The Sharks, Saturday's match provides the ideal opportunity to finish the season on a high.
"If you look at the Kings, they've played pretty well this season and they gave the Stormers a bit of a fright last Saturday," said Reece-Edwards.
"When we played them last, we thought it might have been a bit easier and we were perhaps a bit too conservative and made too many mistakes. They've proven that they are a tough side to beat, they don't give up and have the best tackle percentage in the competition.
"With that in mind, we can really expect a hard game. In two weeks' time they also have a promotion-relegation match, but we can't worry about whether or not that might be in the back of their minds."
"We've got to think about one thing and that's this game, and then from there it's a new campaign."
Victory for the Southern Kings this weekend would be their first in Super Rugby over a South African side.
The Bookies have given the Kings a 23 point start for this Match - with an offer of a FREE $150 BET. The Sharks should win this match by 15+.
This Match will be shown on TV in NZ, Aus, SA and in the UK on Sky Sports 4/HD.
Average score: Sharks 21 Southern Kings 12
09 Mar 2013 Sharks v Kings 21-12 Port Elizabeth
Sharks record against the Kings
Played 1 ,Wins 1 ,Losses 0 ,Draws 0
Match No.119 :Sharks v Kings
Date : Saturday 13 July
Venue : Kings Park, Durban
Kick Off local: 17:05
Referee: Jonathan Kaplan
Assistant Ref 1:Marius Jonker
Assistant Ref 2:Reuben Roussow
TMO : Shaun Veldsman
1. Tendai Mtawarira , 2. Bismarck du Plessis , 3. Jannie du Plessis, 4. Edwin Hewitt, 5. Franco van der Merwe, 6. Marcell Coetzee, 7. Jean Deysel, 8. Keegan Daniel (Captain), 9. Charl McLeod, 10. Riaan Viljoen, 11. Lwazi Mvovo, 12. Meyer Bosman , 13. Louis Ludik, 14. JP Pietersen, 15. Odwa Ndungane
Replacements: 16. Kyle Cooper, 17. Wiehahn Herbst, 18. Jandre Marais, 19. Willem Alberts , 20. Jacques Botes, 21. Cobus Reinach, 22. Fred Zeilinga
Siviwe Soyizwapi, Marcello Sampson, Waylon Murray, Shane Gates, Hadleigh Parkes, George Whitehead, Nicolas Vergallo, Charl du Plessis, Hannes Franklin, Kevin Buys, Devin Oosthuizen, Steven Sykes (captain), David Bulbring, Mpho Mbiyozo, Jacques Engelbrecht.
Replacements: Grant Kemp, Bandise Maku, Darron Nell, Thabo Mamojele, Aidon Davis, Shaun Venter, Michael Killian.