The Reds have been forced into making a change to their team to face the Waratahs as Mike Harris has been ruled out due to an ankle injury.
Harris will be replaced by Anthony Fainga'a at inside centre, who will start his first game of the season for the Reds. Ben Lucas comes into the match-day 23 as a replacement on the reserves bench.
Harris pulled up fine from the Reds' 27-17 win over the Brumbies last weekend and trained well early in the week, but complained of ankle soreness after weights this morning.
He missed morning training to go for a scan on the ankle and has since been ruled out.
1. James Slipper , 2. Saia Fainga'a , 3. Greg Holmes , 4. Rob Simmons , 5. James Horwill (C) , 6. Eddie Quirk , 7. Liam Gill , 8. Jake Schatz , 9. Will Genia (VC) , 10. Quade Cooper , 11. Dom Shipperley , 12. Anthony Fainga'a , 13. Ben Tapuai , 14. Lachie Turner , 15. Aidan Toua
Replacements : 16. James Hanson , 17. Ben Daley , 18. Jono Owen , 19. Ed O'Donoghue , 20. Beau Robinson , 21. Nick Frisby , 22. Ben Lucas , 23. Chris Feauai-Sautia