The Sharks have named an unchanged starting line up to face the Lions at Ellis Park on Saturday with Paul Jordaan returning to the team through the replacement bench.
Sharks Director of Rugby Jake White has retained all but one of the 23 players that beat the Waratahs two weeks ago before they had their bye last week.
Paul Jordaan has recovered from his injury and is named on the bench which pushes Heimar Williams out of the 23-man squad.
Odwa Ndungane will win his 100th Super Rugby cap in the clash.
The Lions lost to the Crusaders at Ellis Park last weekend but White said that they will not be reading anything into the Lions loss.
"People will say they're disappointed, but the truth is, the Crusaders have won the title seven times. They are generally a team that starts late, they tend to hit their straps later in the competition, and the worst time to play them is in the middle of the tournament. So I don't think we need to read too much into the fact that the Lions lost to the Crusaders. "
"Yes, they'll be disappointed because they have been going along well, but to lose to the Crusaders is not doom or gloom for anybody."
White said that he expects the Lions forwards to test his Sharks pack in a typical South African derby where the two packs look to assert dominance over one another.
"The Lions' forward pack has been outstanding, I think Johan Ackermann has done a fantastic job. He talks about it often and he's right, he has an inexperienced front row that took on a team like the Auckland Blues who have three All Blacks playing and next week they're up against a Reds' side with three Wallabies playing there.
"Their front row was supposedly young players who've come along and staked a claim," said White on the Sharks site.
"That's just three players in a whole team, but it epitomises everybody in that group: no-namers who have really stuck their hands up and played above themselves.
"And then they have a lot of pace in the backline and a lot of skills, and the fact that Elton Jantjies, a Springbok, isn't in their starting line-up proves that they're obviously quite comfortable with the way they're playing. Last time we played them, Elton started against us. Now he's not in the mix, so it will be a completely different challenge for us."
15. Lwazi Mvovo , 14. Odwa Ndungane , 13. S'bura Sithole , 12. Frans Steyn , 11. JP Pietersen , 10. Fred Zeilinga , 9. Charl McLeod , 8. Ryan Kankowski , 7. Jean Deysel , 6.Marcell Coetzee , 5. Stephan Lewies , 4. Willem Alberts , 3. Jannie du Plessis , 2. Bismarck du Plessis (Captain) , 1. Tendai Mtawarira
Replacements , 16. Kyle Cooper , 17. Dale Chadwick , 18. Lourens Adriaanse , 19. Etienne Oosthuizen br> 20. Keegan Daniel , 21. Stefan Ungerer , 22. Paul Jordaan , 23. SP Marais