Saracens have named their team to play in the Aviva Premiership Semi-final against Harlequins at Allianz Park on Saturday.
Steve Borthwick will play his final home game for the club and captains the side from lock forward, where he is partnered by Mouritz Botha in the second row.
Elsewhere in the pack, Matt Stevens comes into the side at tighthead prop, and is joined by Schalk Brits and Mako Vunipola in the front row.
Jacques Burger starts at openside flanker, with Scotland captain Kelly Brown and England No.8 Billy Vunipola completing the back row.
In the backs, Neil de Kock partners Owen Farrell at half-back. In the midfield Brad Barritt and Marcelo Bosch start in the centres.
Alex Goode starts at full-back with David Strettle and Chris Ashton starting on the wings.
Saracens are playing in a fifth successive Aviva Premiership Rugby semi-final, their second at Allianz Park, but have not been victorious at this stage since beating Gloucester at Vicarage Road in 2011.
Saracens only home defeat in the Premiership this season was to London Irish in round 13.
Harlequins have reached three successive Premiership semi-finals but their only victory came at home to Northampton in 2012.
'Quins solo defeat in their last seven matches in all tournaments came at Northampton in the semi-final of the European Challenge Cup on 25th April.
Harlequins lone victory in their last ten fixtures with Saracens was 24-19 at Wembley Stadium in March 2012.
The two sides have met only twice before in a knock-out tie, both were played at the Stoop, and both won by Harlequins in the fourth round of the Pilkington Cup in 1994 and the quarter final of the same competition three years later.
Meanwhile Harlequins have named Nick Easter to start at number 8 and becomes the club's most professionally capped player, surpassing Ceri Jones' record of 232 appearances.
There is just one change to the team which beat Bath Rugby as Luke Wallace recovers from an injury to start at blindside flanker in place of Maurie Fa'asavalu who picked up a knock during last week's victory.
The Bookies have given Harlequins an 8 point start for this Match - with an offer of a FREE £200.00 Bet. Open an account, make a deposit of £10 or more and you will be entitled to a 100% bonus on your qualifying deposit up to a maximum of £200.
Match : Saracens v Harlequins
Date : Saturday 17 May
Venue : Allianz Park,
Kick Off : 2pm
Live on: BT Sport
Referee: Wayne Barnes (139th Premiership game).
Assistant Referees: Robin Goodliffe and Roy Maybank.
TMO: Graham Hughes.
15. Alex Goode; 14. Chris Ashton, 13. Marcelo Bosch, 12. Brad Barritt, 11. David Strettle; 10. Owen Farrell, 9. Neil de Kock; 1. Mako Vunipola, 2. Schalk Brits, 3. Matt Stevens, 4. Steve Borthwick ©, 5. Mouritz Botha, 6. Kelly Brown, 7. Jacques Burger, 8. Billy Vunipola.
Replacements: 16. Jamie George, 17. Richard Barrington, 18. James Johnston, 19. Alistair Hargreaves, 20. Jackson Wray, 21. Richard Wigglesworth, 22. Charlie Hodgson, 23. Chris Wyles.
15. Mike Brown, 14. Tom Williams, 13. Tim Molenaar, 12. Jordan Turner-Hall, 11. Ugo Monye, 10. Nick Evans, 9. Danny Care , 8. Nick Easter , 7. Chris Robshaw (C) , 6. Luke Wallace , 5. George Robson , 4. Charlie Matthews , 3. Kyle Sinckler , 2. Dave Ward, 1. Joe Marler
Replacements :16. Rob Buchanan, 17. Mark Lambert, 18. Will Collier, 19. Nick Kennedy, 20. Tom Guest, 21. Karl Dickson, 22. Ben Botica, 23. Sam Smith