Rebels captain Stirling Mortlock says that while he was happy with the Rebels effort, he was left frustrated with his team's inability to put an 80-minute performance together on the night.
The Rebels lost 37-32 to the Lions at Coca-Cola Park in Johannesburg after leading 25-32 in the final quarter.
The victory would have been the Rebels first ever win on foreign soil but instead they were left frustrated that they let the match slip away.
"A little disappointed with the result but happy with the way the guys fought their way back in the second-half," said Mortlock.
"But at this level, when you allow a team to get away to that kind of start, it's very difficult to get back into the game.
"We came here to get the win, so we're very disappointed.
"We're happy with certain aspects of the game but it's the inconsistency that is really frustrating at the moment."
The Lions raced out to a 24-0 lead late in the first-half and it looked like the Rebels might be on the end of a hiding, but a try on the stroke of half-time by hooker Ged Robinson gave his team the confidence to make a sensational second-half comeback.
The Rebels went in front in the final quarter but minutes later Lions replacement Jaco Kriel crossed in the corner to tie the scores up at 32-all before Jantjies made no mistake with the conversion to wrestle the lead back with just six minutes to go.
One last chance for the Rebels to begin an attack deep in their own half went begging when a pass was pushed forward and out, the Lions taking advantage just a couple of phases later when Jantjies kicked a penalty goal to wrap the game up 37-32 for the home team.