Reds captain James Horwill has ruled himself out of his team's Super Rugby match against the Hurricanes this weekend due to his continuing ankle problem.
Horwill injured his left ankle during training before the Super Rugby season had started and he has missed both of the Reds Super Rugby matches in 2013.
The Reds captain missed the end of the 2012 Super Rugby season - as well as the Wallabies season - after suffering a serious hamstring tear.
The Brumbies expected Horwill to play in the Super Rugby opener in Canberra two weeks ago but the plan was for him to play against the Waratahs last weekend.
The twenty-seven-year-old Reds captain will now have to wait until next week at least before he gets on to the field.
The Reds host the Hurricanes as Suncorp this weekend and travel to Melbourne to take on the Rebels next weekend in Round Four.
"I won't be playing this week," Horwill who was wearing a moonboot told Sky News.
"It's been a little bit frustrating but (the moon boot is) hopefully coming off by Tuesday and then I can get back into it.
"We're hopeful I can get back in the next couple of weeks but we just need to see what the response is to running.
"I ran last week and pulled up a little bit sore so hence the reason I went back into the boot to try and de-load it a bit and take a bit of the pressure off while walking around."
The Wallabies captain says that he is confident that the injury is not worse than he first thought it to be and says that his latest setback will not impact on his chances of facing the British and Irish Lions in June and July.
"I hope so, that's the plan," Horwill said when asked if he'll be fit and firing in time for the first Test in Brisbane on June 22.
"First I just have to get on the field, it's been a long time off for me but there's still a lot of rugby to be played.
"We've only had two rounds of Super Rugby so there's plenty of footy to play and I'm hoping not to be out for too much longer but when I get back and make sure that I'm still playing to my ability that I know I can then we'll see where that goes from there."
Meanwhile Will Genia says that he is on track to return in around a month and is confident that he will be fit to face the British and Irish Lions.
Genia missed the second half of last year's Rugby season after he tore his anterior cruciate ligament playing for the Wallabies against South Africa in the Rugby Championship during September.
"At this stage hopefully round five or round six, the whole rehab process has gone really well and really smoothly," Genia said of his likely return date.
"I've also got to tick off a few boxes and start doing contact as of this afternoon so hopefully everything goes well."
Twenty-five-year-old Genia did however say that he would not rush his return as it would risk a further injury.
"I think it's really important (to be patient), not just for the Lions series but in terms of my well being as a player moving forward," he said.
"I spoke to James (Horwill) and spoken to a lot of guys who have done their knees previously and they said the worst thing you can do is try to rush back so I'll just go and if it feels right I'll play and if it doesn't I'll give it a few more weeks."