Ireland will be without centre Robbie Henshaw for the third and decisive Test against South Africa on Saturday due to a knee injury.
Henshaw came off late in the second half of Ireland’s loss to South Africa and has returned home to see a specialist.
Ulster centre Luke Marshall is the likely replacement for Henshaw in this week’s Test in Port Elizabeth.
Ireland won the first Test and looked set to win the second test but South Africa surged in the second half and won the match to level the series.